Hormone Optimization
Real medicine with real risk. Shown as clinical territory; never DIY territory.
Proposed mechanism
Bioidentical or synthetic hormone replacement to address documented deficiencies in testosterone, estrogen, progesterone, thyroid, or DHEA. Requires lab monitoring and clinical oversight.
Strongest evidence
Menopausal hormone therapy has extensive trial data (WHI, follow-ups). Testosterone replacement for documented hypogonadism is established. 'Optimization' of normal-range hormones is contested and carries risk.
What's contested or hyped
TRT for men with normal testosterone, pellet therapy protocols, and 'anti-aging hormone clinics' often treat lab numbers rather than symptoms. Risks include cardiovascular events, clotting, and fertility effects.
Biome describes modalities; it does not recommend protocols, products, or providers. Consult qualified clinicians for medical decisions.