Information, not medical advice. Not a substitute for clinical care. All modeled outputs are conditional estimates, not predictions.

Nervous System

Breathwork

Autonomic nervous system modulation; oldest modality on the list with the newest data.

Proposed mechanism

Controlled breathing patterns influence the vagus nerve, heart rate variability, CO2 tolerance, and autonomic balance between sympathetic and parasympathetic systems.

Strongest evidence

RCTs demonstrate HRV improvements, anxiety reduction, and stress biomarker changes. Box breathing, cyclic sighing, and Wim Hof breathing have the most study. Accessible, free, no equipment required.

Biome describes modalities; it does not recommend protocols, products, or providers. Consult qualified clinicians for medical decisions.